Warriors 1st Grader
- May 7, 2012
A selection of the latest research on the new coronavirus.www.nature.com
13 November — The coronavirus can mutate swiftly in one person’s body
The new coronavirus resurged again and again in the body of an infected man, eventually killing him while showing evidence of fast-paced evolution.
Manuela Cernadas and Jonathan Li at Brigham and Women’s Hospital in Boston, Massachusetts, and their colleagues followed the course of COVID-19 in a 45-year-old man with a long-standing autoimmune disorder, who was on a medication regimen that included powerful immunosuppressants (B. Choi et al. N. Engl. J. Med. https://doi.org/fhv8; 2020). Roughly 40 days after the man first tested positive for SARS-CoV-2, follow-up tests indicated that the virus was dwindling — but it surged back, despite antiviral treatment.
The man’s infection subsided and then returned twice more before he died, five months after his first COVID-19 diagnosis. Genomic analysis showed that the man had not been infected multiple times. Instead, the virus had lingered and quickly mutated in his body.
Of late there have been at least three sensational media Covid releases.
Potential Vaccine resistent Covid mutation from Minks.
Covid was circulating much earlier than previously thought.
And this report of a one off case in a reputable publication of an apparent rapid mutation.
The Mink story while potentially alarming has nothing to suggest other than theory that it is Vaccine resistant.
However it would be a good idea for Denmark to close its borders until this outbreak is extinguished, they are not doing that.
The story about early covid cases looks true on the surface, but nowhere in the article is the term genomic testing mention (after being convinced yesterday I went back and re read it today) without genomics that story is rubbish.
But this case was genomically tracked we are told, so that is good science and more of a concern.
However it may still prove to be an anomaly since this person who died had some form of compromise to their immunity and apart from this one case, the virus is mutating at a fairly predictable and steady slow rate.
We will just have to wait and see.
I expect there will be other stories. Hopefully none of them prove a wider problem.